Cytokeratin 7 (CK7) is a cytoplasmic intermediate filament protein expressed on most ductal and glandular epithelium including lung, breast, bladder and the female genital tract, but not in most gastrointestinal epithelium, prostate, hepatocyte and squamous epithelium. CK7 expression is absent in colon cancer, prostate cancer and squamous carcinomas. CDX-2 is a transcription factor that is expressed in the intestine. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer.
Cytokeratin 7 (CK7) is a cytoplasmic intermediate filament protein expressed on most ductal and glandular epithelium including lung, breast, bladder and the female genital tract, but not in most gastrointestinal epithelium, prostate, hepatocyte and squamous epithelium. CK7 expression is absent in colon cancer, prostate cancer and squamous carcinomas. CDX-2 is a transcription factor that is expressed in the intestine. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer.
Cytokeratin 7 (CK7) is a cytoplasmic intermediate filament protein expressed on most ductal and glandular epithelium including lung, breast, bladder and the female genital tract, but not in most gastrointestinal epithelium, prostate, hepatocyte and squamous epithelium. CK7 expression is absent in colon cancer, prostate cancer and squamous carcinomas. CDX-2 is a transcription factor that is expressed in the intestine. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer.
