HER2 / ErbB2 is one of four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases. The kinase activity of ErbB2 can be activated without a ligand if it is overexpressed, and by association with other ErbB proteins. HER2 is overexpressed in 25-30% of all breast cancers, including primary as well as metastatic breast tumors. HER2 has been widely investigated as a prognostic indicator. Detection of phosphorylated HER2 may aid in predicting breast cancer progression.
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HER2 / ErbB2 Phospho (pY877) (EP123)
Rabbit Monoclonal
HER2 / ErbB2 is one of four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases. The kinase activity of ErbB2 can be activated without a ligand if it is overexpressed, and by association with other ErbB proteins. HER2 is overexpressed in 25-30% of all breast cancers, including primary as well as metastatic breast tumors. HER2 has been widely investigated as a prognostic indicator. Detection of phosphorylated HER2 may aid in predicting breast cancer progression.
Rabbit Monoclonal
HER2 / ErbB2 is one of four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases. The kinase activity of ErbB2 can be activated without a ligand if it is overexpressed, and by association with other ErbB proteins. HER2 is overexpressed in 25-30% of all breast cancers, including primary as well as metastatic breast tumors. HER2 has been widely investigated as a prognostic indicator. Detection of phosphorylated HER2 may aid in predicting breast cancer progression.
