Trefoil factor 3 (TFF3) is a member of the trefoil family. Trefoil factors (TFFs) constitute a family of mucin-associated peptides containing one or more structurally characteristic trefoil domains. They are mainly synthesized and secreted by mucin secreting epithelial cells lining the gastrointestinal tract and have a close association with mucins. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. TFF3 is expressed in goblet cells of the intestines and colon, eptihelial cells of the breast, prostate, thyroid, salivary gland and urinary tract.
Literature:
Manufacturer site:
TFF3 (EP107)
Rabbit Monoclonal
Trefoil factor 3 (TFF3) is a member of the trefoil family. Trefoil factors (TFFs) constitute a family of mucin-associated peptides containing one or more structurally characteristic trefoil domains. They are mainly synthesized and secreted by mucin secreting epithelial cells lining the gastrointestinal tract and have a close association with mucins. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. TFF3 is expressed in goblet cells of the intestines and colon, eptihelial cells of the breast, prostate, thyroid, salivary gland and urinary tract.
Rabbit Monoclonal
Trefoil factor 3 (TFF3) is a member of the trefoil family. Trefoil factors (TFFs) constitute a family of mucin-associated peptides containing one or more structurally characteristic trefoil domains. They are mainly synthesized and secreted by mucin secreting epithelial cells lining the gastrointestinal tract and have a close association with mucins. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. TFF3 is expressed in goblet cells of the intestines and colon, eptihelial cells of the breast, prostate, thyroid, salivary gland and urinary tract.