Adenovirus infection is associated with a broad spectrum of clinical disease in both children and adults. It has gained more attention as an important complication in patients who have undergone bone marrow or solid organ transplantation. The incidence of adenovirus infection in bone marrow transplant patients has been reported at 5-20%. Adenovirus infection on morphology should be differentially diagnosed from other virus infections, especially CMV infection. Anti-adenovirus can assist in this differential diagnosis by showing a round or crescent-shaped nuclear inclusion, generally within the surface epithelium and is exclusively intra-nuclear in location.
Adenovirus infection is associated with a broad spectrum of clinical disease in both children and adults. It has gained more attention as an important complication in patients who have undergone bone marrow or solid organ transplantation. The incidence of adenovirus infection in bone marrow transplant patients has been reported at 5-20%. Adenovirus infection on morphology should be differentially diagnosed from other virus infections, especially CMV infection. Anti-adenovirus can assist in this differential diagnosis by showing a round or crescent-shaped nuclear inclusion, generally within the surface epithelium and is exclusively intra-nuclear in location.
http://www.cellmarque.com/Cell Marque
Adenovirus infection is associated with a broad spectrum of clinical disease in both children and adults. It has gained more attention as an important complication in patients who have undergone bone marrow or solid organ transplantation. The incidence of adenovirus infection in bone marrow transplant patients has been reported at 5-20%. Adenovirus infection on morphology should be differentially diagnosed from other virus infections, especially CMV infection. Anti-adenovirus can assist in this differential diagnosis by showing a round or crescent-shaped nuclear inclusion, generally within the surface epithelium and is exclusively intra-nuclear in location.
