CD4 is a 55 kD glycoprotein expressed on the surface of T-helper/regulatory T-cells, monocytes, macrophages, and dendritic cells. Anti-CD4 is used in the immunophenotyping of lymphoproliferative disorders.1 The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+ CD8-.2 As with other T-cell antigens, CD4 may be aberrantly expressed in neoplastic T-cells so that the evaluation of such tumors requires the application of a panel of markers in order to identify tumors with CD4 aberrant expression.1-3
1. Leong AS-Y, et al. Greenwich Medical Media Ltd. 2003.
2. Akiyama T, et al. Pathol Int. 2008; 58:626-34.
3. Garcia-Herrera A, et al. J Clin Oncol. 2008; 26:3364-71.
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CD4 (EP204)
Rabbit Monoclonal
CD4 is a 55 kD glycoprotein expressed on the surface of T-helper/regulatory T-cells, monocytes, macrophages, and dendritic cells. Anti-CD4 is used in the immunophenotyping of lymphoproliferative disorders.1 The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+ CD8-.2 As with other T-cell antigens, CD4 may be aberrantly expressed in neoplastic T-cells so that the evaluation of such tumors requires the application of a panel of markers in order to identify tumors with CD4 aberrant expression.1-3
1. Leong AS-Y, et al. Greenwich Medical Media Ltd. 2003.
2. Akiyama T, et al. Pathol Int. 2008; 58:626-34.
3. Garcia-Herrera A, et al. J Clin Oncol. 2008; 26:3364-71.
Rabbit Monoclonal
CD4 is a 55 kD glycoprotein expressed on the surface of T-helper/regulatory T-cells, monocytes, macrophages, and dendritic cells. Anti-CD4 is used in the immunophenotyping of lymphoproliferative disorders.1 The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4+ CD8-.2 As with other T-cell antigens, CD4 may be aberrantly expressed in neoplastic T-cells so that the evaluation of such tumors requires the application of a panel of markers in order to identify tumors with CD4 aberrant expression.1-3
1. Leong AS-Y, et al. Greenwich Medical Media Ltd. 2003.
2. Akiyama T, et al. Pathol Int. 2008; 58:626-34.
3. Garcia-Herrera A, et al. J Clin Oncol. 2008; 26:3364-71.
